Kyle Chandler as Sherman Peabody (Max Charles voices Sherman's pull string voicebox)

Henry Cavill as Jimmy Neutron(Debbi Derryberry voices Jimmy's button activated voice box)

Peri Gilplin as Mabel Pines

Steven Colbert as Toothless

Patrick Warburton as Gene Belcher

Rob Paulsen as Gumball Watterson

Charlize Theron as Dani Phantom

Tom Kenny as Spongebob

Noah Schnapp as Trent Cooper
George Newbern as Trent's Dad
Ellen Degenres as Trent's Mom
Zach Callison as Duncan
Christopher Ayres as Frieza
Clancy Brown as Lex Luthor
Vic Microgna as Broly
Dameon Clarke as Perfect Cell
TBA as Dr. Octagonapus
Jim Cummings as Cat
Tom Kenny as Dog