It's war.Everyone has aligned themselves with either Konoha or Uchiha Madara. Those caught by the enemy are forced into mental enslavement. Tsunade sends Sakura to find a cure but on the way she ends up finding something else su/Saku

Naruto loses control.With no options left,Tsunade orders Sakura to help recede the Kyuubi. The effect leaves her comatose for a year. When she awakes she must deal with the changes that have occurred – starting with the return of a specific Uchiha.SasuSak

Marriage. In most cases it comes with the joys of pregnancy. For Sakura, it's become a goal. For Sasuke, Sakura is his only goal. Sasu/Saku